Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
Anti-CRISPR proteins offer the means of regulating CRISPR-Cas9 activity. Here the authors present the structure and biochemical characterisation of AcrIIC2 Nme alone and in complex with Cas9.
Bibliographic Details
| Main Authors: |
Annoj Thavalingam,
Zhi Cheng,
Bianca Garcia,
Xue Huang,
Megha Shah,
Wei Sun,
Min Wang,
Lucas Harrington,
Sungwon Hwang,
Yurima Hidalgo-Reyes,
Erik J. Sontheimer,
Jennifer Doudna,
Alan R. Davidson,
Trevor F. Moraes,
Yanli Wang,
Karen L. Maxwell |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2019-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-10577-3
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