Plasmid-Mediated Transmission of KPC-2 Carbapenemase in Enterobacteriaceae in Critically Ill Patients

Carbapenem-resistant Enterobacteriaceae (CRE) cause health care-associated infections worldwide, and they are of severe concern due to limited treatment options. We report an outbreak of KPC-2-producing CRE that was caused by horizontal transmission of a promiscuous plasmid across different genera o...

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Bibliographic Details
Main Authors: Christian Schweizer, Peter Bischoff, Jennifer Bender, Axel Kola, Petra Gastmeier, Manfred Hummel, Frank-Rainer Klefisch, Felix Schoenrath, Andre Frühauf, Yvonne Pfeifer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
WGS
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00276/full