Conjugation of metronidazole with dextran: a potential pharmaceutical strategy to control colonic distribution of the anti-amebic drug susceptible to metabolism by colonic microbes

Wooseong Kim, Yejin Yang, Dohoon Kim, Seongkeun Jeong, Jin-Wook Yoo, Jeong-Hyun Yoon, Yunjin Jung Laboratory of Biomedicinal Chemistry, Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan, Republic of Korea Abstract: Metronidazole (MTDZ), the drug of choice...

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Bibliographic Details
Main Authors: Kim W, Yang Y, Kim D, Jeong S, Yoo J, Yoon JH, Jung Y
Format: Article
Language:English
Published: Dove Medical Press 2017-02-01
Series:Drug Design, Development and Therapy
Subjects:
Online Access:https://www.dovepress.com/conjugation-of-metronidazole-with-dextran-a-potential-pharmaceutical-s-peer-reviewed-article-DDDT