An important role of PHRF1 in dendritic architecture and memory formation by modulating TGF-β signaling

Abstract PHRF1 is involved in transforming growth factor β (TGF-β) signaling to constrain the formation of acute promyelocytic leukemia (APL) in mouse APL models. PHRF1 also participates in modulating non-homologous end-joining. However, the role of PHRF1 in mammalian dendrite architecture and synap...

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Bibliographic Details
Main Authors: Ting-Wei Shih, Li-Jen Lee, Ho-Ching Chang, Hung-Wei Lin, Mau-Sun Chang
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-67675-2