An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10

<p>Abstract</p> <p>Background</p> <p>A major challenge lies in understanding the complexities of gene regulation. Mutation of the transcription factor SOX10 is associated with several human diseases. The disease phenotypes reflect the function of SOX10 in diverse tissue...

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Bibliographic Details
Main Authors: Pavan William J, Rodrigues Frederico SLM, Carney Thomas J, Antonellis Anthony, Dutton James R, Ward Andrew, Kelsh Robert N
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/8/105