Mutagenicity testing with transgenic mice. Part II: Comparison with the mouse spot test

<p>Abstract</p> <p>The mouse spot test, an <it>in vivo </it>mutation assay, has been used to assess a number of chemicals. It is at present the only <it>in vivo </it>mammalian test system capable of detecting somatic gene mutations according to OECD guidelin...

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Bibliographic Details
Main Authors: Wahnschaffe Ulrich, Bitsch Annette, Kielhorn Janet, Mangelsdorf Inge
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2005-01-01
Series:Journal of Carcinogenesis
Online Access:http://www.carcinogenesis.com/content/4/1/4