N–O Cleavage reactions of heterobicycloalkene-fused 2-isoxazolines

Transition metal-mediated N–O bond cleavage reactions of heterobicycloalkene-fused 3-methyl-2-isoxazolines were investigated. Optimal cleavage conditions were found with Raney nickel/AlCl3 mediation in aqueous methanol. The reaction provided a diverse collection of novel heterobicycle-fused β-hydrox...

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Bibliographic Details
Main Authors: Jaipal R. Nagireddy, Geoffrey K. Tranmer, Emily Carlson, William Tam
Format: Article
Language:English
Published: Beilstein-Institut 2014-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.10.227