Numbers of mutations to different types of colorectal cancer

<p>Abstract</p> <p>Background</p> <p>The numbers of oncogenic mutations required for transformation are uncertain but may be inferred from how cancer frequencies increase with aging. Cancers requiring more mutations will tend to appear later in life. This type of approa...

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Bibliographic Details
Main Authors: Tavaré Simon, Aaltonen Lauri A, Järvinen Heikki J, Mecklin Jukka-Pekka, Calabrese Peter, Shibata Darryl
Format: Article
Language:English
Published: BMC 2005-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/126