Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Abstract Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial b...

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Bibliographic Details
Main Authors: Hanna Ungewiß, Franziska Vielmuth, Shintaro T. Suzuki, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Daniela Kugelmann, Nicolas Schlegel, Jens Waschke
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06713-y

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https://doi.org/10.1038/s41598-017-06713-y

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