Genotoxic action of the sesquiterpene lactone glaucolide B on mammalian cells in vitro and in vivo

Glaucolide B is a sesquiterpene lactone isolated from Vernonia eremophila Mart. (Vernonieae, Asteraceae) and has schistosomicidal, antimicrobial and analgesic activities. This study examined the cytotoxic and clastogenic activities of glaucolide B in human cultured lymphocytes and in bone marrow cel...

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Bibliographic Details
Main Authors: Regislaine V. Burim, Renata Canalle, João L. Callegari Lopes, Catarina S. Takahashi
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 1999-09-01
Series:Genetics and Molecular Biology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000300020