Machine Learning for Detection of Safety Signals From Spontaneous Reporting System Data: Example of Nivolumab and Docetaxel

Machine Learning for Detection of Safety Signals From Spontaneous Reporting System Data: Example of Nivolumab and Docetaxel

Introduction: Various methods have been implemented to detect adverse drug reaction (ADR) signals. However, the applicability of machine learning methods has not yet been fully evaluated.Objective: To evaluate the feasibility of machine learning algorithms in detecting ADR signals of nivolumab and d...

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Bibliographic Details
Main Authors: Ji-Hwan Bae, Yeon-Hee Baek, Jeong-Eun Lee, Inmyung Song, Jee-Hyong Lee, Ju-Young Shin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
disproportionality analysis
nivolumab
docetaxel
signal detection
adverse drug reaction
machine learning algorithms
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.602365/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.602365/full

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