A structural property for reduction of biochemical networks

Abstract Large-scale biochemical models are of increasing sizes due to the consideration of interacting organisms and tissues. Model reduction approaches that preserve the flux phenotypes can simplify the analysis and predictions of steady-state metabolic phenotypes. However, existing approaches eit...

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Bibliographic Details
Main Authors: Anika Küken, Philipp Wendering, Damoun Langary, Zoran Nikoloski
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96835-1