Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation

CD8+ T cells recognize non-self antigen by MHC class I molecules and kill the target cells by the release of proinflammatory cytokines such as interferon gamma (IFN-γ) and tumor necrosis factor alpha (TNF-α). Our group previously reported an increase of CD8+ T‐cell trafficking in the placenta with e...

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Bibliographic Details
Main Authors: Jin Liu, Yang Liu, Snigdha Panda, Anguo Liu, Jun Lei, Irina Burd
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.718563/full