Acetaminophen induces human neuroblastoma cell death through NFKB activation.

Neuroblastoma resistance to apoptosis may contribute to the aggressive behavior of this tumor. Therefore, it would be relevant to activate endogenous cellular death mechanisms as a way to improve neuroblastoma therapy. We used the neuroblastoma SH-SY5Y cell line as a model to study the mechanisms in...

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Bibliographic Details
Main Authors: Inmaculada Posadas, Pablo Santos, Valentín Ceña
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500330?pdf=render