Comprehensive analysis of treatment modes and clinical outcomes of small cell lung cancer transformed from epidermal growth factor receptor mutant lung adenocarcinoma

Comprehensive analysis of treatment modes and clinical outcomes of small cell lung cancer transformed from epidermal growth factor receptor mutant lung adenocarcinoma

Abstract Background Transformation to small cell lung cancer (SCLC) is a resistance mechanism of epidermal growth factor receptor (EGFR) mutant lung adenocarcinoma (LADC) patients treated with EGFR tyrosine kinase inhibitors (TKIs). Here, we describe the clinical characteristics and prognosis of the...

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Bibliographic Details
Main Authors: Shouzheng Wang, Tongji Xie, Xuezhi Hao, Yan Wang, Xingsheng Hu, Lin Wang, Yan Li, Junling Li, Puyuan Xing
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Thoracic Cancer
Subjects:
anti‐angiogenesis
epidermal growth factor receptor mutation
lung adenocarcinoma
small cell histological transformation
tyrosine kinase inhibitors
Online Access:https://doi.org/10.1111/1759-7714.14144

Internet

https://doi.org/10.1111/1759-7714.14144

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