A single mutation in chikungunya virus affects vector specificity and epidemic potential.

Chikungunya virus (CHIKV) is an emerging arbovirus associated with several recent large-scale epidemics. The 2005-2006 epidemic on Reunion island that resulted in approximately 266,000 human cases was associated with a strain of CHIKV with a mutation in the envelope protein gene (E1-A226V). To test...

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Bibliographic Details
Main Authors: Konstantin A Tsetsarkin, Dana L Vanlandingham, Charles E McGee, Stephen Higgs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030201