Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents

To minimize treatment toxicities, recent anti-cancer research efforts have switched from broad-based chemotherapy to targeted therapy, and emerging data show that altered cellular metabolism in cancerous cells can be exploited as new venues for targeted intervention. In this study, we focused on, am...

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Bibliographic Details
Main Authors: Yueqin Yang, Hariprasad Vankayalapati, Manshu Tang, Yingbo Zheng, Yingri Li, Cong Ma, Kent Lai
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/645