Default Mode Network Analysis of APOE Genotype in Cognitively Unimpaired Subjects Based on Persistent Homology

Default Mode Network Analysis of APOE Genotype in Cognitively Unimpaired Subjects Based on Persistent Homology

Current researches on default mode network (DMN) in normal elderly have mainly focused on finding some dysfunctional areas with decreased or increased connectivity. The global network dynamics of apolipoprotein E (APOE) e4 allele group is rarely studied. In our previous brain network study, we have...

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Bibliographic Details
Main Authors: Liqun Kuang, Jiaying Jia, Deyu Zhao, Fengguang Xiong, Xie Han, Yalin Wang, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
APOE
Alzheimer’s disease
persistent homology
resting state functional magnetic resonance imaging
graph theory
network measure
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00188/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2020.00188/full

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