The Kinase Specificity of Protein Kinase Inhibitor Peptide

The Kinase Specificity of Protein Kinase Inhibitor Peptide

G-protein-coupled-receptor (GPCR) signaling is exquisitely controlled to achieve spatial and temporal specificity. The endogenous protein kinase inhibitor peptide (PKI) confines the spatial and temporal spread of the activity of protein kinase A (PKA), which integrates inputs from three major types...

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Bibliographic Details
Main Authors: Yao Chen, Bernardo L. Sabatini
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
protein kinase A
protein kinase C
protein kinase inhibitor peptide
kinase screen
specificity
endogenous
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.632815/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.632815/full

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