Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects

Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects

Abstract Background Contextual effects (i.e., placebo response) refer to all health changes resulting from administering an apparently inactive treatment. In a randomized clinical trial (RCT), the overall treatment effect (i.e., the post-treatment effect in the intervention group) can be regarded as...

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Bibliographic Details
Main Authors: Sigurlaug H. Hafliðadóttir, Carsten B. Juhl, Sabrina M. Nielsen, Marius Henriksen, Ian A. Harris, Henning Bliddal, Robin Christensen
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Trials
Subjects:
Placebo response
Placebo effect
Contextual effects
Proportional contextual effect
Online Access:https://doi.org/10.1186/s13063-021-05454-8

Internet

https://doi.org/10.1186/s13063-021-05454-8

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