The Effects on Proliferation of siRNA-Mediated GLS1 Inhibition in MDA-MB 231 Breast Cancer Cells

The main energy source of cancer cells is known as glucose. However, they use glutamine as a second energy source besides glucose. In this study we investigated effect of siRNA mediated inhibition of glutaminase (GLS1) enzyme in the first step of glutamine metabolism on proliferation and apoptosis w...

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Bibliographic Details
Main Authors: Sakine Akar, Zuhal Hamurcu, Hamiyet Donmez-Altuntas
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/40/1/25