C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood–Spinal Cord Barrier

C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood–Spinal Cord Barrier

Neuropathic pain is among the most debilitating forms of chronic pain. Studies have suggested that chronic pain pathogenesis involves neuroimmune interactions and blood–spinal cord barrier (BSCB) disruption. However, the underlying mechanisms are poorly understood. We modeled neuropathic pain in rat...

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Bibliographic Details
Main Authors: Hao-Ling Li, Yan Huang, Ya-Lan Zhou, Run-Hua Teng, Shu-Zhuan Zhou, Jia-Piao Lin, Yan Yang, Sheng-Mei Zhu, Hua Xu, Yong-Xing Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
neuropathic pain
chronic constriction injury
blood–spinal cord barrier
neuroinflammation
behavior
C-X-C motif chemokine 10
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00477/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00477/full

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