Matrine suppresses lipopolysaccharide-induced fibrosis in human peritoneal mesothelial cells by inhibiting the epithelial-mesenchymal transition

Abstract. Background:. Peritoneal fibrosis is the primary reason that patients with end-stage renal disease (ESRD) have to cease peritoneal dialysis. Peritonitis caused by Gram-negative bacteria such as Escherichia coli (E. coli) were on the rise. We had previously shown that matrine inhibited the...

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Bibliographic Details
Main Authors: Yi-Zheng Li, Xi Peng, Yun-Hua Ma, Fu-Ji Li, Yun-Hua Liao, Li-Min Chen
Format: Article
Language:English
Published: Wolters Kluwer 2019-03-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000127