Cerebral mechanism of celecoxib for treating knee pain: study protocol for a randomized controlled parallel trial

Abstract Background Celecoxib is frequently prescribed to treat knee osteoarthritis (KOA), but how celecoxib influences the activity of the central nervous system to alleviate chronic pain remains unclear. Methods One hundred eight patients with KOA will be enrolled in this study. Patients will be a...

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Bibliographic Details
Main Authors: Chenjian Tang, Xiaohui Dong, Wenhua He, Shirui Cheng, Yang Chen, Yong Huang, Bao Yin, Yu Sheng, Jun Zhou, Xiaoli Wu, Fang Zeng, Zhengjie Li, Fanrong Liang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-018-3111-8