LncRNA ENSMUST00000155383 is Involved in the Improvement of DPP-4 Inhibitor MK-626 on Vascular Endothelial Function by Modulating Cacna1c-Mediated Ca2+ Influx in Hypertensive Mice

LncRNA ENSMUST00000155383 is Involved in the Improvement of DPP-4 Inhibitor MK-626 on Vascular Endothelial Function by Modulating Cacna1c-Mediated Ca2+ Influx in Hypertensive Mice

Objective: This study investigated the protective effects of dipeptidyl peptidase-4 inhibitor MK-626 on vascular endothelial function by regulating lncRNAs in hypertensive vasculature.Methods: Angiotensin Ⅱ (Ang Ⅱ)-loaded osmotic pumps were implanted in mice with or without MK-626 administration. GL...

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Bibliographic Details
Main Authors: Yi Zhang, Na Tan, Yi Zong, Li Li, Yan Zhang, Jian Liu, Xiaorui Wang, Wenwen Han, Limei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
calcium
endothelial function
glucagon-like peptide-1
hypertension
long noncoding RNA
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.724225/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.724225/full

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