Toll-Like Receptor Signaling and Liver Fibrosis

Liver fibrosis occurs as a wound-healing scar response following acute and chronic liver inflammation including alcoholic liver disease, non-alcoholic steatohepatitis, hepatitis B and C, and autoimmune hepatitis. Myofibroblasts, mainly transdifferentiated from hepatic stellate cells, are pivotal cel...

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Bibliographic Details
Main Authors: Tomonori Aoyama, Yong-Han Paik, Ekihiro Seki
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/192543