Influence of lipopolysaccharides on autophagy and inflammation in pancreatic islet cells of mice fed by high-fat diet

The aim of this study was to confirm whether chronic low-grade inflammation could induce autophagy and damage in islet cells. The high-fat diet (HF) and low-dose lipopolysaccharides (LPS) were used to simulate chronic inflammation. Islet function was observed, the expression of autophagy-related pro...

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Bibliographic Details
Main Authors: Hongwei Jiang, Yujin Ma, Liujun Fu, Jie Wang, Linlei Wang, Menglin Fan, Ke Huang, Yingyu Zhang, Huifang Peng
Format: Article
Language:English
Published: SAGE Publishing 2018-01-01
Series:International Journal of Immunopathology and Pharmacology
Online Access:https://doi.org/10.1177/1721727X17754180