Total Synthesis of Phorbazole B

Total Synthesis of Phorbazole B

Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the trichlorinated phorbazole B using late stage electrophilic chlorination was dev...

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Bibliographic Details
Main Authors:	Yngve Guttormsen, Magnus E. Fairhurst, Sunil K. Pandey, Johan Isaksson, Bengt Erik Haug, Annette Bayer
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Molecules
Subjects:	phorbazole oxazole pyrrole late-stage chlorination
Online Access:	https://www.mdpi.com/1420-3049/25/20/4848

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