Total Synthesis of Phorbazole B

Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the trichlorinated phorbazole B using late stage electrophilic chlorination was dev...

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Bibliographic Details
Main Authors: Yngve Guttormsen, Magnus E. Fairhurst, Sunil K. Pandey, Johan Isaksson, Bengt Erik Haug, Annette Bayer
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/20/4848