Inefficient skeletal muscle oxidative function flanks impaired motor neuron recruitment in Amyotrophic Lateral Sclerosis during exercise

Abstract This study aimed to evaluate muscle oxidative function during exercise in amyotrophic lateral sclerosis patients (pALS) with non-invasive methods in order to assess if determinants of reduced exercise tolerance might match ALS clinical heterogeneity. 17 pALS, who were followed for 4 months,...

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Bibliographic Details
Main Authors: F. Lanfranconi, A. Ferri, G. Corna, R. Bonazzi, C. Lunetta, V. Silani, N. Riva, A. Rigamonti, A. Maggiani, C. Ferrarese, L. Tremolizzo
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02811-z