Neurotensin and CRH interactions augment human mast cell activation.

Stress affects immunity, but the mechanism is not known. Neurotensin (NT) and corticotropin-releasing hormone (CRH) are secreted under stress in various tissues, and have immunomodulatory actions. We had previously shown that NT augments the ability of CRH to increase mast cell-dependent skin vascul...

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Bibliographic Details
Main Authors: Konstantinos-Dionysios Alysandratos, Shahrzad Asadi, Asimenia Angelidou, Bodi Zhang, Nikolaos Sismanopoulos, Hailing Yang, Agatha Critchfield, Theoharis C Theoharides
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23155429/pdf/?tool=EBI