Centrosome clustering and cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumors

<p>Abstract</p> <p>Background</p> <p>Aneuploidy, centrosome abnormalities and gene amplification are hallmarks of chromosome instability (CIN) in cancer. Yet there are no studies of the <it>in vivo </it>behavior of these phenomena within the same bladder tum...

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Bibliographic Details
Main Authors: Camps Jordi, Algaba Ferran, Gelabert Antoni, Lloreta Josep, Ponsa Immaculada, Prat Esther, del Rey Javier, Miró Rosa
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/280