Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells

Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells

Abstract Background Gram-positive bacteria stimulate Toll-like receptor (TLR) 2 and then activate the pro-inflammatory nuclear factor-kappa B (NF-κB) pathway. As the human ocular surface is heavily colonised by gram-positive cocci bacteria, a balance of activation/repression of NF-κB target genes is...

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Bibliographic Details
Main Authors: Aihua Hou, Min Qi Tin, Louis Tong
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Eye and Vision
Subjects:
TLR2
NF-κB pathway
Activation
Ocular surface cells
Online Access:http://link.springer.com/article/10.1186/s40662-017-0082-x

Internet

http://link.springer.com/article/10.1186/s40662-017-0082-x

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