Chemical Exchange Saturation Transfer MRI Signal Loss of the Substantia Nigra as an Imaging Biomarker to Evaluate the Diagnosis and Severity of Parkinson's Disease

Chemical Exchange Saturation Transfer MRI Signal Loss of the Substantia Nigra as an Imaging Biomarker to Evaluate the Diagnosis and Severity of Parkinson's Disease

The early diagnosis of Parkinson's disease (PD) and the accurate evaluation of disease severity are crucial for intervention and treatment in PD patients. In this study, we applied chemical exchange saturation transfer (CEST) imaging to patients at different stages of PD and explored the clinic...

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Bibliographic Details
Main Authors: Chunmei Li, Min Chen, Xuna Zhao, Rui Wang, Haibo Chen, Wen Su, Shuhua Li, Baohui Lou, Guodong Song, Shuai Zhang, Jintao Zhang, Jinyuan Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neuroscience
Subjects:
CEST imaging
APT imaging
biomarker
substantia nigra
Parkinson's disease
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00489/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00489/full

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