ALADDIN study: does assisted hatching of vitrified/warmed blastocysts improve live birth rate? Protocol for a multicentric randomised controlled trial

Introduction Recent data suggest a higher clinical pregnancy rate performing assisted hatching (AH) on previously cryopreserved embryos but fail to demonstrate significant effects on live birth rate. However, current evidence is based on studies with a small sample size and may hide a type II error....

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Main Authors: Alessandra Alteri, Cristina Guarneri, Laura Corti, Liliana Restelli, Marco Reschini, Paolo Giardina, Enrico Papaleo, Edgardo Somigliana, Paola Viganò, Alessio Paffoni
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/7/e031544.full