Robust taxonomic classification of uncharted microbial sequences and bins with CAT and BAT

Abstract Current-day metagenomics analyses increasingly involve de novo taxonomic classification of long DNA sequences and metagenome-assembled genomes. Here, we show that the conventional best-hit approach often leads to classifications that are too specific, especially when the sequences represent...

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Bibliographic Details
Main Authors: F. A. Bastiaan von Meijenfeldt, Ksenia Arkhipova, Diego D. Cambuy, Felipe H. Coutinho, Bas E. Dutilh
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1817-x