Extended Combined Neonatal Treatment With Erythropoietin Plus Melatonin Prevents Posthemorrhagic Hydrocephalus of Prematurity in Rats

Extended Combined Neonatal Treatment With Erythropoietin Plus Melatonin Prevents Posthemorrhagic Hydrocephalus of Prematurity in Rats

Posthemorrhagic hydrocephalus of prematurity (PHHP) remains a global challenge. Early preterm infants (<32 weeks gestation), particularly those exposed to chorioamnionitis (CAM), are prone to intraventricular hemorrhage (IVH) and PHHP. We established an age-appropriate, preclinical model of P...

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Bibliographic Details
Main Authors: Shenandoah Robinson, Fatu S. Conteh, Akosua Y. Oppong, Tracylyn R. Yellowhair, Jessie C. Newville, Nagat El Demerdash, Christine L. Shrock, Jessie R. Maxwell, Stephen Jett, Frances J. Northington, Lauren L. Jantzie
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
intraventricular hemorrhage (IVH)
chorioamnionitis
neurorepair
ventriculomegaly
diffusion tensor imaging (DTI)
preterm
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00322/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00322/full

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