Acidic pH Triggers Lipid Mixing Mediated by Lassa Virus GP

Lassa virus (LASV) is the causative agent of Lassa hemorrhagic fever, a lethal disease endemic to Western Africa. LASV entry is mediated by the viral envelope glycoprotein (GP), a class I membrane fusogen and the sole viral surface antigen. Previous studies have identified components of the LASV ent...

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Bibliographic Details
Main Authors: Uriel Bulow, Ramesh Govindan, James B. Munro
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/7/716