The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients

The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients

Abstract Background BRAF mutations occur in 2–4% non-small cell lung cancer (NSCLC) patients and can be categorized into three functional classes based on signaling mechanism and kinase activity: RAS-independent kinase-activating V600 monomers (class 1), RAS-independent kinase-activating dimers (cla...

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Bibliographic Details
Main Authors: Quan Lin, Haoran Zhang, Huaxin Ding, Jun Qian, Analyn Lizaso, Jing Lin, Han Han-Zhang, Jianxing Xiang, Yuping Li, Hong Zhu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Translational Medicine
Subjects:
BRAF
Non-small cell lung cancer
Chinese
Online Access:http://link.springer.com/article/10.1186/s12967-019-2036-7

Internet

http://link.springer.com/article/10.1186/s12967-019-2036-7

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