Discovery Strategies to Maximize the Clinical Potential of T-Cell Engaging Antibodies for the Treatment of Solid Tumors

T-cell Engaging bispecific antibodies (TcEs) that can re-direct cytotoxic T-cells to kill cancer cells have been validated in clinical studies. To date, the clinical success with these agents has mainly been seen in hematologic tumor indications. However, an increasing number of TcEs are currently b...

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Bibliographic Details
Main Authors: Vladimir Voynov, Paul J. Adam, Andrew E. Nixon, Justin M. Scheer
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/9/4/65