The role of Wnt/β-catenin-lin28a/let-7 axis in embryo implantation competency and epithelial-mesenchymal transition (EMT)

The role of Wnt/β-catenin-lin28a/let-7 axis in embryo implantation competency and epithelial-mesenchymal transition (EMT)

Abstract Background The pre-implantation embryo in a competent status and post-implantation fully differentiation of the inner cell mass (ICM) and trophectoderm (TE) are prerequisites of successful implantation. Type I embryonic epithelial-mesenchymal transition (EMT) involves in these processes. A...

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Bibliographic Details
Main Authors: Qian Li, Juanzi Shi, Weimin Liu
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cell Communication and Signaling
Subjects:
Wnt/β-catenin signaling
Lin28a protein
Mir-let-7 family
Implantation competency
Embryonic EMT
Online Access:http://link.springer.com/article/10.1186/s12964-020-00562-5

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http://link.springer.com/article/10.1186/s12964-020-00562-5

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