Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study

Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study

Immune response to a given antigen, particularly in cancer patients, is complex and is controlled by various genetic and environmental factors. Identifying biomarkers that can predict robust response to immunization is an urgent need in clinical cancer vaccine development. Given the involvement of D...

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Bibliographic Details
Main Authors: Cinthia Violeta Hernandez Puente, Ping-Ching Hsu, Lora J. Rogers, Fariba Jousheghany, Eric Siegel, Susan A. Kadlubar, J. Thaddeus Beck, Issam Makhoul, Laura F. Hutchins, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
DNA methylation
breast cancer
cancer vaccine
immune response
pilot study
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00879/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00879/full

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