Role of heparan sulfate in mediating CXCL8-induced endothelial cell migration

CXCL8 (Interleukin-8, IL-8) plays an important role in angiogenesis and wound healing by prompting endothelial cell migration. It has been suggested that heparan sulfate (HS) could provide binding sites on endothelial cells to retain and activate highly diffusible cytokines and inflammatory chemokin...

Full description

Bibliographic Details
Main Authors: Zhiping Yan, Jingxia Liu, Linshen Xie, Xiaoheng Liu, Ye Zeng
Format: Article
Language:English
Published: PeerJ Inc. 2016-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1669.pdf