Quantifying <i>BRCA1</i> and <i>BRCA2</i> mRNA Isoform Expression Levels in Single Cells

Quantifying <i>BRCA1</i> and <i>BRCA2</i> mRNA Isoform Expression Levels in Single Cells

<i>BRCA1</i> and <i>BRCA2</i> spliceogenic variants are often associated with an elevated risk of breast and ovarian cancers. Analyses of <i>BRCA1</i> and <i>BRCA2</i> splicing patterns have traditionally used technologies that sample a population of c...

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Bibliographic Details
Main Authors: Vanessa L. Lattimore, John F. Pearson, Arthur E. Morley-Bunker, kConFab Investigators, Amanda B. Spurdle, Bridget A. Robinson, Margaret J. Currie, Logan C. Walker
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
splicing
single cell
mRNA expression
<i>BRCA1</i>
<i>BRCA2</i>
RNAscope
Online Access:https://www.mdpi.com/1422-0067/20/3/693

Internet

https://www.mdpi.com/1422-0067/20/3/693

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