The cystic fibrosis lung microenvironment alters antibiotic activity: causes and effects
Chronic airway colonisation by Pseudomonas aeruginosa, a hallmark of cystic fibrosis (CF) lung disease, is associated with increased morbidity and mortality and despite aggressive antibiotic treatment, P. aeruginosa is able to persist in CF airways. In vitro antibiotic susceptibility assays are poor...
Main Authors: | Sara Van den Bossche, Emma De Broe, Tom Coenye, Eva Van Braeckel, Aurélie Crabbé |
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Format: | Article |
Language: | English |
Published: |
European Respiratory Society
2021-09-01
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Series: | European Respiratory Review |
Online Access: | http://err.ersjournals.com/content/30/161/210055.full |
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