The cystic fibrosis lung microenvironment alters antibiotic activity: causes and effects

Chronic airway colonisation by Pseudomonas aeruginosa, a hallmark of cystic fibrosis (CF) lung disease, is associated with increased morbidity and mortality and despite aggressive antibiotic treatment, P. aeruginosa is able to persist in CF airways. In vitro antibiotic susceptibility assays are poor...

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Bibliographic Details
Main Authors: Sara Van den Bossche, Emma De Broe, Tom Coenye, Eva Van Braeckel, Aurélie Crabbé
Format: Article
Language:English
Published: European Respiratory Society 2021-09-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/30/161/210055.full