MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: understanding their physiological function through post-genomic approaches

Multidrug/Multixenobiotic resistance (MDR/MXR) is a widespread phenomenon with clinical, agricultural and biotechnological implications, where MDR/MXR transporters that are presumably able to catalyze the efflux of multiple cytotoxic compounds play a key role in the acquisition of resistance. Howeve...

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Bibliographic Details
Main Authors: Sandra C. dos Santos, Miguel Cacho Teixeira, Paulo J. Dias, Isabel eSá-Correia
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00180/full