The ciliary protein Ftm is required for ventricular wall and septal development.

Ventricular septal defects (VSDs) are the most common congenital heart defects in humans. Despite several studies of the molecular mechanisms involved in ventricular septum (VS) development, very little is known about VS-forming signaling. We observed perimembranous and muscular VSDs in Fantom (Ftm)...

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Bibliographic Details
Main Authors: Christoph Gerhardt, Johanna M Lier, Stefanie Kuschel, Ulrich Rüther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585374?pdf=render