Activation of Cryptic Antibiotic Biosynthetic Gene Clusters Guided by RNA-seq Data from Both <i>Streptomyces ansochromogenes</i> and ΔwblA

Activation of Cryptic Antibiotic Biosynthetic Gene Clusters Guided by RNA-seq Data from Both <i>Streptomyces ansochromogenes</i> and ΔwblA

With the increase of drug resistance caused by the improper use and abuse of antibiotics, human beings are facing a global health crisis. Sequencing of <i>Streptomyces</i> genomes revealed the presence of an important reservoir of secondary metabolic gene clusters for previously unsuspec...

Full description

Bibliographic Details
Main Authors: Yue Li, Haiying Yu, Hanye Guan, Jingjing Li, Jihui Zhang, Hua Xiang, Jine Li, Huarong Tan
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
RNA-seq analysis
<i>Streptomyces</i>
cryptic gene cluster
tylosin analogue compounds 1,2,3 (TACs)
oviedomycin
Online Access:https://www.mdpi.com/2079-6382/10/9/1097

Internet

https://www.mdpi.com/2079-6382/10/9/1097

Similar Items