Protective Effect of Edaravone Against Oxidative Stress in C2C12 Myoblast and Impairment of Skeletal Muscle Regeneration Exposed to Ischemic Injury in Ob/ob Mice

Protective Effect of Edaravone Against Oxidative Stress in C2C12 Myoblast and Impairment of Skeletal Muscle Regeneration Exposed to Ischemic Injury in Ob/ob Mice

BackgroundThe aims of this study were to analyze the effects of the administration of edaravone on C2C12 myoblasts exposed to oxidative stress; to evaluate the skeletal muscles in ob/ob mice; and to analyze the effect of the administration of edaravone in the regeneration of skeletal muscle after is...

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Bibliographic Details
Main Authors: Takuya Nakanishi, Masaya Tsujii, Takahiro Asano, Takahiro Iino, Akihiro Sudo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
skeletal muscle
obesity
oxidative stress
myoblast
free radical scavenger
edaravone
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01596/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01596/full

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